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Polychlorinated biphenyls in indoor dust from urban dwellings of Lahore, Pakistan: Congener profile, toxicity equivalency, and human health implications
Indoor Air ( IF 5.8 ) Pub Date : 2021-01-18 , DOI: 10.1111/ina.12788
Iqra Aslam 1 , Mujtaba Baqar 2 , Abdul Qadir 1 , Mehvish Mumtaz 1 , Jun Li 3 , Gan Zhang 3
Affiliation  

This study is the pioneer assessment of the PCBs in indoor dust particles (from air conditioners) of an urbanized megacity from South Asian. The ∑35 PCB concentration ranged from 0.27 to 152.9 ng/g (mean: 24.84 ± 22.10 ng/g). The tri- and tetra-PCBs were dominant homologues, contributing 57.36% of the total PCB concentrations. The mean levels of Σ8-dioxin-like (DL), Σ6-indicator PCBs and WHO2005-TEQ for DL-PCBs were 2.22 ± 2.55 ng/g, 9.49 ± 8.04 ng/g and 4.77 ± 4.89 pg/g, respectively. The multiple linear regression indicated a significant correlation of dusting frequency (p = 1.06 × 10–04) and age of the house (p = 1.02 × 10–06) with PCB concentrations in indoor environment. The spatial variation of PCB profile revealed relatively higher concentrations from sites near to illegal waste burning spots, electrical locomotive workshops, and grid stations. Human health risk assessment of PCBs for adults and toddlers through all three exposure routes (ie, inhalation, ingestion, and dermal contact) demonstrated that toddlers were vulnerable to high cancer risk (4.32 × 10−04), while adults were susceptible from low to moderate levels of risk (3.16 × 10−05). Therefore, comprehensive investigations for PCBs in the indoor settings, focusing particularly on the sensitive populations with relationship to the electronic devices, transformers, and illegal waste burning sites, are recommended.

中文翻译:

巴基斯坦拉合尔城市住宅室内灰尘中的多氯联苯:同系物特征、毒性等效性和人类健康影响

这项研究是对南亚城市化大都市室内灰尘颗粒(来自空调)中多氯联苯的先驱性评估。∑ 35 PCB 浓度范围为 0.27 至 152.9 ng/g(平均值:24.84 ± 22.10 ng/g)。三和四多氯联苯是主要的同系物,占总多氯联苯浓度的 57.36%。Σ 8 -类二恶英 (DL)、Σ 6 -指示剂 PCB 和 WHO 2005 -TEQ 的 DL-PCB的平均水平分别为 2.22 ± 2.55 ng/g、9.49 ± 8.04 ng/g 和 4.77 ± 4.89 pg/g,分别。多元线性回归表明除尘频率(p  = 1.06 × 10–04)和房屋年龄(p = 1.02 × 10–06) 室内环境中的 PCB 浓度。PCB 分布的空间变化表明,靠近非法垃圾焚烧点、电力机车车间和电网站的地点的浓度相对较高。通过所有三种暴露途径(即吸入、摄入和皮肤接触)对成人和幼儿多氯联苯的人类健康风险评估表明,幼儿易患高癌症风险(4.32 × 10 -04),而成年人易患癌症的风险从低到高。中等风险水平(3.16 × 10 -05)。因此,建议对室内环境中的多氯联苯进行全面调查,特别关注与电子设备、变压器和非法废物焚烧场所有关的敏感人群。
更新日期:2021-01-18
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