The multicomponent synthesis of 1-amidoalkyl naphthols and polyhydroquinolines has been developed as an atom-economic procedure catalyzed by a deep eutectic solvent ([CholineCl][ZnCl₂]₃). The reactions proceed smoothly at low temperatures for a short reaction time without the use of toxic and volatile organic solvents. Deep eutectic solvents are capable of not only allowing multicomponent reactions to proceed in high yield but also controlling the selectivity towards desired products. The mechanistic insight was examined by HRMS (ESI) to propose a plausible mechanism. Furthermore, [CholineCl][ZnCl₂]₃ can be recycled in up to three consecutive cycles with an insignificant loss of catalytic activity under the optimized conditions.

中文翻译：

---

用深共熔溶剂一锅三组分合成1-酰胺基烷基萘酚和多氢喹啉：一种绿色方法和机理研究

作为一种由深共熔溶剂（[CholineCl] [ZnCl ₂ ] ₃）催化的原子经济方法，已经开发了1-酰胺基烷基萘酚和聚氢喹啉的多组分合成方法。反应在低温下可在短时间内反应平稳进行，而无需使用有毒和挥发性的有机溶剂。深共晶溶剂不仅能够使多组分反应以高收率进行，而且能够控制对所需产物的选择性。该机制的见解由HRMS（ESI）进行了审查，以提出一个合理的机制。此外，[CholineCl] [ZnCl ₂ ] ₃可以在最优化的条件下以多达三个连续循环的方式循环利用，而催化活性的损失却很小。