Annals of Allergy, Asthma & Immunology ( IF 5.9 ) Pub Date : 2021-01-17 , DOI: 10.1016/j.anai.2021.01.014 Joanna S. Zeiger , William S. Silvers , Tonya A. Winders , Mary K. Hart , Robert S. Zeiger
Background
Cannabis use in patients with allergy/asthma, a high-risk group for adverse effects to cannabis, is unknown.
Objective
To determine the patterns of use and attitudes toward cannabis in patients with allergy/asthma.
Methods
An anonymous online survey on cannabis attitudes and use was conducted through the Adult Allergy & Asthma Network. The Asthma Control Test assessed asthma burden. Cluster analyses determined group phenotypes and factor analyses condensed cannabis subjective effects into similar response patterns.
Results
A total of 88 of 489 respondents (18.0%) currently use cannabis with most at the age of less than 50 years old, of female sex, and of White race. Of the noncannabis users (N = 401), 2.5% reported cannabis allergy. Cluster analysis revealed that a liberal attitude toward cannabis was associated with current cannabis use (P < .001). Among current cannabis users, 40.9% of their physicians inquired on cannabis use; only 37.5% of users wanted to discuss cannabis. In addition, 65.9% used cannabis for medical or medical/recreational purposes. Cannabinoids used were tetrahydrocannabinol (33.0%), cannabidiol (19.3%), or both (47.7%). Smoked and vaped cannabis were reported by 53.4% and 35.2%, respectively. Furthermore, 51 cannabis users (58.0%) reported current asthma with 39.2% uncontrolled; of these, 50% smoked cannabis. Compared with current participants with asthma not using cannabis, those currently using cannabis experienced similar levels of asthma control, quality of life, and frequency of asthma exacerbations. Positive effects were endorsed more than negative effects to cannabis (P < .001). Moreover, 19.3% of cannabis users reported coughing that was associated with smoking cannabis (P < .001).
Conclusion
Cannabis was used by less than 20% of the respondents with positive effects more frequent than negative effects. Half of cannabis users with uncontrolled asthma smoke cannabis, but only a minority of the physicians inquire about its use.
中文翻译:
过敏和哮喘网络追随者中的大麻态度和使用方式
背景
对于过敏/哮喘患者(对大麻有不良影响的高风险人群),大麻的使用尚不明确。
客观的
确定过敏/哮喘患者使用大麻的方式和对大麻的态度。
方法
通过成人过敏和哮喘网络对大麻的态度和用途进行了匿名在线调查。哮喘控制测试评估了哮喘负担。聚类分析确定了小组的表型,因素分析将大麻的主观效果浓缩为相似的反应模式。
结果
目前,在489位受访者中,有88位(18.0%)目前使用的大麻中,大多数年龄小于50岁,女性和白人。在非大麻使用者中(N = 401),有2.5%的人报告了大麻过敏。聚类分析表明,对大麻的自由态度与当前的大麻使用有关(P<.001)。在目前的大麻使用者中,有40.9%的医生询问了大麻的使用情况;只有37.5%的用户想要讨论大麻。此外,有65.9%的大麻用于医疗或医疗/娱乐目的。所使用的大麻素为四氢大麻酚(33.0%),大麻二酚(19.3%)或两者(47.7%)。据报告,抽烟的和抽出的大麻分别为53.4%和35.2%。此外,有51名大麻使用者(58.0%)报告说目前患有哮喘,其中39.2%未得到控制。其中,有50%的烟熏大麻。与当前不使用大麻的哮喘患者相比,当前使用大麻的患者哮喘控制水平,生活质量和哮喘发作频率相似。对大麻的积极影响大于对大麻的消极影响(P<.001)。此外,有19.3%的大麻使用者报告了与吸烟大麻有关的咳嗽(P <.001)。
结论
不到20%的受访者使用大麻,积极作用比消极作用更频繁。患有不受控制的哮喘的大麻使用者中有一半吸食大麻,但只有少数医生询问其使用情况。