Deep space exploration missions need strategies to mitigate the potentially harmful exposure to galactic cosmic radiation. This form of radiation can cause significant damage to biological systems and organisms, which include radiation-induced carcinogenesis in the hematopoietic system. Ongoing studies investigate these effects using cell- and animal-based studies in low earth orbit. The logistic challenges and costs involved with sending biological specimens to space have prompted the development of surrogate ground-based radiation experiments to study the mechanisms of biological injury and cancer risk. However, simulating galactic cosmic radiation has proven difficult and current studies are only partially succeeding at replicating the complexity of this radiation and its downstream injury pathways. Accurate simulation of chronic, low dose galactic radiation will improve our ability to test mitigation strategies such as drug development and improved shielding materials that could be crucial and essential for successful space exploration.

深空探索任务需要策略来减轻对银河宇宙辐射的潜在有害暴露。这种形式的辐射会对生物系统和生物体造成重大损害，包括造血系统中辐射诱发的致癌作用。正在进行的研究使用基于细胞和动物的近地轨道研究来调查这些影响。将生物标本送入太空所涉及的后勤挑战和成本促使开发了替代地面辐射实验，以研究生物损伤和癌症风险的机制。然而，模拟银河宇宙辐射已被证明是困难的，目前的研究仅部分成功地复制了这种辐射的复杂性及其下游损伤途径。准确模拟慢性，