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Biocompatibility and Bioresorption of 3D-Printed Polylactide and Polyglycolide Tissue Membranes
Bulletin of Experimental Biology and Medicine ( IF 0.7 ) Pub Date : 2021-01-01 , DOI: 10.1007/s10517-021-05066-x
E V Kim 1 , Y S Petronyuk 2 , N A Guseynov 1 , S V Tereshchuk 3 , A A Popov 3 , A V Volkov 1 , V N Gorshenev 2 , A A Olkhov 2 , V M Levin 2 , A B Dymnikov 1 , V E Rodionov 1 , G A Tumanyan 1 , S G Ivashkevich 1 , A P Bonartsev 3 , L L Borozdkin 4
Affiliation  

We studied biocompatibility and bioresorption of 3D-printed polylactide and polyglycolide tissue membranes. Ultrasound microscopy and histological examination showed that membranes fabricated of a copolymer of lactic and glycolic acids in a mass ratio of 1:9 are bioresorbed and have good biocompatibility with soft tissues (connective tissue, adipose tissue, and epithelium). An important feature of the copolymer membranes, which differs them from pure polylactide membranes, is the formation of a thin fibrous capsule that did not interfere its destruction by the mechanism of hydrolytic resorption.

中文翻译:

3D 打印聚乳酸和聚乙交酯组织膜的生物相容性和生物再吸收

我们研究了 3D 打印的聚丙交酯和聚乙交酯组织膜的生物相容性和生物再吸收。超声显微镜和组织学检查表明,由质量比为 1:9 的乳酸和乙醇酸共聚物制成的膜具有生物再吸收性,并且与软组织(结缔组织、脂肪组织和上皮)具有良好的生物相容性。共聚物膜与纯聚丙交酯膜不同的一个重要特征是形成一个薄的纤维胶囊,不会通过水解再吸收机制干扰其破坏。
更新日期:2021-01-01
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