Adrenergic innervation in the tissue of the cervical, mesenteric, and popliteal lymph nodes in rats of different age groups (from 2-45 days to 24 months) was studied using the specific fluorescence-microscopic imaging of catecholamines. Adrenergic innervation in the lymph nodes of rats is present from the first days of life, but it develops and complicates during postnatal ontogeny and is fully formed by thedays 20-30 of life. By the age of one month, adrenergic innervation represents a well-formed apparatus in all parts of the node, i.e. in the capsule, trabeculae, and cortical and medullary substance. These are brightly fluorescent nerve fibers that form plexuses with regularly located multiple varicosities. In senile animals, the density and number of plexuses in all parts of the lymph node are preserved, but the brightness of plexuses decreases, plexus fibers become discontinuous, varicosities become less frequent or disappear. These changes are seen in lymph nodes from different body regions.

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年轻、成熟和老年动物不同身体区域淋巴结的肾上腺素能神经支配的特性

使用儿茶酚胺的特异性荧光显微成像研究了不同年龄组（从 2-45 天到 24 个月）大鼠颈部、肠系膜和腘淋巴结组织中的肾上腺素能神经支配。大鼠淋巴结中的肾上腺素能神经支配从生命的最初几天就存在，但它在出生后个体发育过程中发展和复杂化，并在生命的 20-30 天完全形成。到 1 个月大时，肾上腺素能神经支配在结节的所有部分，即在囊、小梁、皮质和髓质物质中表现出良好的结构。这些是发出明亮荧光的神经纤维，形成具有规则定位的多个静脉曲张的神经丛。在老年动物中，淋巴结所有部位的神经丛密度和数量都保持不变，但神经丛的亮度降低，神经丛纤维变得不连续，静脉曲张变得不那么频繁或消失。这些变化可见于身体不同部位的淋巴结。