Mechanisms underlying the promotion of 5-hydroxytryptamine secretion in enterochromaffin cells of constipation mice by Bifidobacterium and Lactobacillus,Neurogastroenterology & Motility

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Mechanisms underlying the promotion of 5-hydroxytryptamine secretion in enterochromaffin cells of constipation mice by Bifidobacterium and Lactobacillus
Neurogastroenterology & Motility ( IF 3.5 ) Pub Date : 2021-01-15 , DOI: 10.1111/nmo.14082
Youyou Lu ₁ , Zhe Zhang ₁ , Lingjun Tong ₁ , Xiaohong Zhou ₂ , Xi Liang ₁ , Huaxi Yi ₁ , Pimin Gong ₁ , Tongjie Liu ₁ , Lanwei Zhang ₁ , Liuqing Yang ₃ , Hanping Shi ₃

Affiliation

5-Hydroxytryptamine (5-HT) could play a role in alleviating symptoms in constipation. However, the mechanism underlying the role of intestinal flora in the promotion of 5-HT secretion by enterochromaffin cells (ECs) and regulation of the gastrointestinal endocrine system remains unclear.

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