We aim to evaluate urinary total BPA (tBPA) levels and association with medical devices used on patients in pediatric intensive care units. This cross-sectional descriptive study included 117 critically ill children. Urinary tBPA levels were determined using high-performance liquid chromatography. General estimating equations with repeated measures analyzed the effect of interventions and devices on urinary BPA levels. A total of 292 urine samples taken from 117 child intensive care patients were studied. When age, sex, and body mass index-for age z-scores were controlled, cases having endotracheal intubation showed higher urinary tBPA levels (p = 0.003) and hemodialyzed patients had considerably higher urinary tBPA levels (p = 0.004). When confounding factors were controlled, cases using both multiple iv treatment and more than four medical devices showed higher urinary tBPA levels than their counterparts (p = 0.007 and p = 0.028, respectively). The use of certain medical devices and interventions could increase BPA exposure in pediatric intensive care patients.

我们旨在评估儿科重症监护病房患者尿液总BPA（tBPA）水平以及与医疗设备的关联。这项横断面描述性研究包括117名重症儿童。使用高效液相色谱法测定尿液中的tBPA水平。重复测量的通用估计方程分析了干预措施和设备对尿液BPA水平的影响。研究人员从117名儿童重症监护患者中采集了292份尿液样本。当控制年龄，性别和体重指数（针对z分数）时，气管内插管患者的尿液tBPA水平较高（p = 0.003），血液透析患者的尿液tBPA水平较高（p = 0.004）。当混杂因素得到控制后，同时使用多次静脉治疗和多于四种医疗设备的病例，其尿中的tBPA水平高于同龄患者（分别为p = 0.007和p = 0.028）。使用某些医疗设备和干预措施可能会增加小儿重症监护患者的BPA暴露。