Autism is a complex neurodevelopmental broad-spectrum disorder characterized by social interaction, and aberrant restrictive and repetitive behavior. The complex pathophysiology and unexplored drug targets make it difficult to standardize and validate the animal models of autism. The review was purposed for determining the benefits of younger animal models over adult models of autism. Similarly, animal models with respect to age, sex, body weight, number of animals used, along with autism inducing agents have been reviewed in this article. The differentiation of behavioral parameters has shown the benefits in the selection of younger animal models. Thus, we conclude that young and adolescence animal models of autism will be supporting for early detection and interventions with significant results.

自闭症是一种复杂的神经发育广谱障碍，其特征是社交互动、异常限制性和重复性行为。复杂的病理生理学和未经探索的药物靶点使得自闭症动物模型的标准化和验证变得困难。该综述的目的是确定年轻动物模型相对于成年自闭症模型的益处。同样，本文对动物模型的年龄、性别、体重、使用的动物数量以及自闭症诱导剂进行了综述。行为参数的差异显示了选择年轻动物模型的好处。因此，我们得出的结论是，年轻和青春期自闭症动物模型将支持早期检测和干预，并取得显着效果。