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Parent‐reported Autism Diagnostic Stability and Trajectories in the Longitudinal Study of Australian Children
Autism Research ( IF 4.7 ) Pub Date : 2021-01-14 , DOI: 10.1002/aur.2470
Tamara May 1, 2 , Amanda Brignell 1, 2, 3 , Katrina Williams 1, 2, 3, 4
Affiliation  

This study aimed to explore the stability of parent‐reported diagnosis of Autism Spectrum Disorder (ASD) and factors influencing the trajectories in two cohorts from the prospective Longitudinal Study of Australian Children (LSAC). Parent‐reported ASD diagnosis was collected for children from 6 years of age in a Birth cohort and 10 years of age in a Kinder cohort; allowing for exploration of diagnostic stability at age 6, 8, 10, and 12 years (Birth cohort) and 10, 12, 14, 16 years (Kinder cohort). Children were grouped based on persisting, desisting, inconsistent and late (diagnosis after 6 years—Birth cohort; after 10 years—Kinder) subgroups over four timepoints. Multinomial logistic regression explored predictors of diagnostic trajectories; generalized estimating equations examined trajectories of emotional and behavioral problems. Of 66 Birth cohort children parent‐reported to have ASD at age 6, with data at all four time points, 14% did not at 12 years; of 73 Kinder cohort children at age 10 years, 26% no longer had parent‐reported ASD at 16 years. Children with late diagnoses showed increasing trajectories of emotional and behavioral problems, while children with persisting or desisting diagnoses showed decreasing trajectories. Between 86% and 74% had a reported ASD diagnosis after 6 years. Findings indicate that children with ASD need services and supports that can adapt to their changing needs, which may be increasing, decreasing or different. This has implications for the provision of services and funding.

中文翻译:

父母报告的澳大利亚儿童纵向研究中的自闭症诊断稳定性和轨迹

这项研究旨在探讨前瞻性澳大利亚儿童纵向研究(LSAC)在两个队列中父母报告的自闭症谱系障碍(ASD)诊断的稳定性以及影响轨迹的因素。父母报告的ASD诊断是针对出生队列中6岁以下和Kinder队列中10岁以下的儿童收集的;允许探索6、8、10和12岁(出生队列)和10、12、14、16岁(金德队列)的诊断稳定性。根据持续,坚持,前后不一致(6岁后诊断为出生队列; 10年后诊断为Kinder)在四个时间点上对儿童分组。多项式逻辑回归探索了诊断轨迹的预测因子;广义估计方程考察了情绪和行为问题的轨迹。父母报告称66岁的出生队列儿童在6岁时有ASD,所有四个时间点都有数据,其中14%的人在12岁时没有。在73岁的10岁Kinder队列儿童中,有26%的人在16岁时不再有父母报告的ASD。诊断较晚的儿童表现出情绪和行为问题的轨迹增加,而诊断持续或缺乏的孩子则表现出下降的轨迹。6年后,有86%至74%的患者报告了ASD诊断。研究结果表明,患有自闭症的儿童需要可以适应不断变化的需求的服务和支持,这些需求可能会增加,减少或有所不同。这对提供服务和资金有影响。26%的人在16岁时不再有父母报告的ASD。诊断较晚的儿童表现出情绪和行为问题的轨迹增加,而诊断持续或缺乏的孩子则表现出下降的轨迹。6年后,有86%至74%的患者报告了ASD诊断。研究结果表明,患有自闭症的儿童需要可以适应不断变化的需求的服务和支持,这些需求可能会增加,减少或有所不同。这对提供服务和资金有影响。26%的人在16岁时不再有父母报告的ASD。诊断晚的儿童表现出情绪和行为问题的轨迹增加,而诊断持续或缺乏的孩子表现出的轨迹下降。6年后,有86%至74%的患者报告了ASD诊断。研究结果表明,患有自闭症的儿童需要可以适应不断变化的需求的服务和支持,这些需求可能会增加,减少或有所不同。这对提供服务和资金有影响。研究结果表明,患有自闭症的儿童需要可以适应不断变化的需求的服务和支持,这些需求可能会增加,减少或有所不同。这对提供服务和资金有影响。研究结果表明,患有自闭症的儿童需要可以适应不断变化的需求的服务和支持,这些需求可能会增加,减少或有所不同。这对提供服务和资金有影响。
更新日期:2021-01-14
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