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Sweet talk: Metabolic conversations between host and microbe during infection
Immunology ( IF 6.4 ) Pub Date : 2021-01-14 , DOI: 10.1111/imm.13301
Eyal Amiel 1 , Georgia Perona-Wright 2
Affiliation  

In this issue, we introduce the second part of a series of reviews focusing on how immunometabolism influences host and pathogen interactions during infection. This part of the collection addresses the interface between metabolism and specific types of infection, including immunometabolism in macrophages during helminth infection, the role of metabolism in T‐cell exhaustion during chronic viral infections and host immunometabolism in the defence against Mycobacterium tuberculosis infection. These reviews, together with the four articles published in part 1 of the series in November 2020, offer new insights into the complex interactions between mammalian hosts and microbial pathogens through the lens of cellular metabolic regulation.

中文翻译:

甜言蜜语:感染期间宿主与微生物之间的代谢对话

在本期中,我们将介绍一系列综述的第二部分,重点关注免疫代谢如何影响感染期间的宿主和病原体相互作用。这部分集合讨论了新陈代谢与特定类型感染之间的界面,包括蠕虫感染期间巨噬细胞中的免疫代谢、慢性病毒感染期间新陈代谢在 T 细胞耗竭中的作用以及宿主免疫代谢在防御结核分枝杆菌感染中的作用。这些评论以及 2020 年 11 月在该系列的第 1 部分中发表的四篇文章,通过细胞代谢调控的视角,为哺乳动物宿主与微生物病原体之间的复杂相互作用提供了新的见解。
更新日期:2021-01-14
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