Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting elderly people (>60 years old) worldwide. There is no permanent cure for the disease but the symptomatic relief can be obtained by using dopamine agonists besides L‐dopa therapy. The longer use of the drugs is associated with several side effects. Hence, the researchers have made a considerable attention toward the development of neuroprotective agents from plants. A number of phytochemicals have been demonstrated for their protective effects in various in vitro, in vivo, and clinical studies. In this context, luteolin, a flavone which is present in fruits and vegetables has been attributed to a number of pharmacological properties including neuroprotective. The present review demonstrates the bioavailability, oral absorption, and mechanism of action against PD.

中文翻译：

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木犀草素在克服帕金森病中的作用

帕金森病 (PD) 是影响全球老年人（> 60 岁）的第二大最常见的神经退行性疾病。这种疾病没有永久治愈的方法，但除了使用左旋多巴治疗外，还可以使用多巴胺激动剂来缓解症状。药物的长期使用与多种副作用有关。因此，研究人员对从植物中开发神经保护剂给予了相当大的关注。许多植物化学物质已在各种体外、体内和临床研究中被证明具有保护作用。在这种情况下，木犀草素是一种存在于水果和蔬菜中的黄酮，具有许多药理特性，包括神经保护作用。本综述证明了生物利用度、口服吸收、