Ionising radiation interacts with lenses and retinae differently. In human lenses, posterior subcapsular cataracts are the predominant observation, whereas retinae of adults are comparably resistant to even relatively high doses. In this study, we demonstrate the effects of 2 Gy of low linear energy transfer ionising radiation on eyes of B6C3F1 mice aged postnatal day 2. Optical coherence tomography and Scheimpflug imaging were utilised for the first time to monitor murine lenses and retinae in vivo. The visual acuity of the mice was determined and histological analysis was conducted. Our results demonstrated that visual acuity was reduced by as much as 50 % approximately 9 months after irradiation in irradiated mice. Vision impairment was caused by retinal atrophy and inner cortical cataracts. These results help to further our understanding of the risk of ionising radiation for human foeti ($\sim$ 8 mo), which follow the same eye development stages as neonatal mice.

电离辐射与晶状体和视网膜的相互作用不同。在人类晶状体中，后囊下白内障是主要的观察结果，而成人的视网膜对即使相对较高的剂量也具有相当的抵抗力。在这项研究中，我们展示了 2 Gy 低线性能量转移电离辐射对出生后第 2 天的 B6C3F1 小鼠眼睛的影响。光学相干断层扫描和 Scheimpflug 成像首次被用于监测体内小鼠晶状体和视网膜. 测定小鼠的视力并进行组织学分析。我们的结果表明，在接受照射的小鼠中，在照射后大约 9 个月，视力下降了 50%。视力障碍是由视网膜萎缩和内皮层白内障引起的。这些结果有助于我们进一步了解电离辐射对人类胎儿的风险。$～$ 8 mo），它们遵循与新生小鼠相同的眼睛发育阶段。