Prolonged soil moisture deficit poses major threat to plant survival. Plants have evolved to withstand such condition by maintaining water status through adoptive mechanisms. Such mechanisms include modulation of Aquaporins (AQPs) activity. The AQPs are small integral membrane proteins which facilitate water movement across the cells. This review summarizes the important regulatory mechanisms controlling the dynamics of AQP activity to fine tune the plant water status under the water deficit condition. Numerous studies have shown differential AQP expression under drought stress in plants. Among the known AQP subfamilies, members of plasma membrane intrinsic protein (PIP) and tonoplast intrinsic protein (TIP) showed most significant expression under drought condition. The activity, stability, and membrane targeting of these AQPs are known to be regulated at transcriptional as well as post-translational level. Drought induced transcription factors and hormones are also involved in direct or indirect transcriptional regulation. At post-translational level modifications such as phosphorylation, glycosylation, ubiquitination, gating and tetramerization play a role in regulation of the abundance and activity of AQP proteins. Understanding such regulatory mechanisms will help in exploration of AQPs to improve crop plants for sustainable agriculture under changing environmental conditions.

长期的土壤水分缺乏对植物的生存构成重大威胁。植物已经进化为通过过继机制维持水的状态，从而承受这种状况。此类机制包括调节水通道蛋白（AQP）活性。AQP是小的整合膜蛋白，可促进水在细胞中移动。这篇综述总结了在缺水条件下控制AQP活性动态以微调植物水分状况的重要调控机制。大量研究表明，植物在干旱胁迫下的AQP表达差异。在已知的AQP亚家族中，质膜内在蛋白（PIP）和液泡膜内在蛋白（TIP）的成员在干旱条件下表现出最显着的表达。活动性，稳定性，这些AQP的靶向和膜靶向在转录水平和翻译后水平均受到调控。干旱诱导的转录因子和激素也参与直接或间接的转录调控。在翻译后水平上，诸如磷酸化，糖基化，泛素化，门控和四聚化的修饰在调节AQP蛋白的丰度和活性中起作用。理解此类监管机制将有助于探索AQP，以在不断变化的环境条件下改善农作物以实现可持续农业。糖基化，泛素化，门控和四聚化在调节AQP蛋白的丰度和活性中起作用。理解此类监管机制将有助于探索AQP，以在不断变化的环境条件下改善农作物以实现可持续农业。糖基化，泛素化，门控和四聚化在调节AQP蛋白的丰度和活性中起作用。理解此类监管机制将有助于探索AQP，以在不断变化的环境条件下改善农作物以实现可持续农业。