The aim of the study is to compare the results of using innovative normobaric hypoxic training to increase individual's resistance to exogenous hypothermia. Methods: This randomized controlled trial was performed using two groups of men aged 22-34 years. Group 1 (n=9) was exposed to argon-hypoxic training consisting of a 2-hour continuous stay of the test subjects in a gas environment with the composition: Ar 33 % vol., 02 12 % vol., N2 55 %. Group 2 (n=9) was exposed to a normobaric hypoxic training: a 2-hour continuous stay in a nitrogen-containing gas environment, the oxygen content of which decreased from 17 % vol. (1st session) up to 13 % vol. (5th session), after which the composition of the gas environment was not changed. The total number of sessions- 20 conducted daily or after 1-2 days. Training schedules were identical in the two groups. Hypothermic resistance of the subjects was evaluated using 3-minute standard aerocryothermic tests. The activity of the mechanisms of nonspecific protection of the subjects was evaluated by the indicator of serum fibronectin. Results: An improved resistance to hypothermia was observed in both groups. The changes were more pronounced in Group 1. So, with the best subjective resistance to hypothermia exposures in group 1 (p = 0.010-0.014), rectal temperature decrease (p = 0.019) was significantly greater in group 1 than in group 2. Hypereactivity of systemic circulation indicators decreased in Group 1 to a greater extent (p = 0.010-0.038). In addition, with a significant increase in the level of fibronectin in both groups, these changes were significantly (p = 0.014) more pronounced in Group 1. Conclusions: Normobaric hypoxic training in the original regime is a safe and effective method of increasing human resistance to hypothermia. The effectiveness of this method can be improved by conducting argon-hypoxic training developed by the authors.

中文翻译：

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非特定非医疗技术可提高人类对低温的抵抗力

该研究的目的是比较使用创新的常压缺氧训练来增加个体对外源性低温的抵抗力的结果。方法：这项随机对照试验使用两组 22-34 岁的男性进行。第 1 组 (n=9) 接受氩气-缺氧训练，包括测试对象在气体环境中连续停留 2 小时，其成分为：Ar 33% vol.、02 12% vol.、N2 55%。第 2 组 (n=9) 接受常压缺氧训练：在含氮气体环境中连续停留 2 小时，其中氧气含量从 17% vol. （第一节）高达 13 % vol。（第 5 次会议），此后气体环境的成分未发生变化。会话总数 - 每天或 1-2 天后进行 20 次。两组的训练计划相同。使用 3 分钟的标准空气低温测试评估受试者的耐低温性。以血清纤连蛋白为指标评价受试者非特异性保护机制的活性。结果：在两组中均观察到对低温的抵抗力有所改善。第 1 组的变化更为明显。因此，由于第 1 组对低温暴露的主观抵抗力最佳（p = 0.010-0.014），第 1 组的直肠温度下降（p = 0.019）明显大于第 2 组。组 1 中全身循环指标的下降幅度更大（p = 0.010-0.038）。此外，随着两组中纤连蛋白水平的显着增加，这些变化在第 1 组中更为明显（p = 0.014）。结论：原始方案中的常压缺氧训练是一种安全有效的方法，可以提高人体对低温的抵抗力。这种方法的有效性可以通过进行作者开发的氩-缺氧训练来提高。