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Further evidence needed to change policy for the safe and effective radical cure of vivax malaria: Insights from the 2019 annual APMEN Vivax Working Group meeting
Asia & the Pacific Policy Studies ( IF 2.381 ) Pub Date : 2021-01-12 , DOI: 10.1002/app5.314
Varunika Sonani Hapuwatte Ruwanpura 1 , Spike Nowak 2 , Emily Gerth-Guyette 2 , Minerva Theodora 3 , Lek Dysoley 4, 5 , Mebratom Haile 6 , Koen Peeters Grietens 7, 8 , Ric Norman Price 1, 9, 10 , Caroline Anita Lynch 11, 12 , Kamala Thriemer 1
Affiliation  

New diagnostics and treatment options for the radical cure of Plasmodium vivax malaria are now available. At the 2019 annual meeting of the Vivax Working Group of the Asia Pacific Malaria Elimination Network, participants took part in a roundtable discussion to identify further evidence required to introduce these new tools into policy and practice. Key gaps identified were accuracy and reliability of glucose-6-phosphate-dehydrogenase deficiency tests, health system capacity, and feasibility and cost effectiveness of novel treatment strategies in routine clinical practice. As expected, there were differences in the priorities between country partners and researcher partners. To achieve the 2030 target for the regional elimination of malaria, evidence to address these issues should be generated as a matter of priority. Review of global guidelines alongside locally generated data will help to ensure the timely revision and optimisation of national treatment guidelines that will be vital to meet regional elimination goals.

中文翻译:

需要进一步的证据来改变安全有效根治间日疟疾的政策:来自 2019 年年度 APMEN 间日疟疾工作组会议的见解

根治间日疟原虫的新诊断和治疗选择疟疾现在可用。在亚太消除疟疾网络间日疟疾工作组 2019 年年会上,与会者参加了圆桌讨论会,以确定将这些新工具引入政策和实践所需的进一步证据。确定的主要差距是葡萄糖-6-磷酸-脱氢酶缺乏症测试的准确性和可靠性、卫生系统能力以及常规临床实践中新治疗策略的可行性和成本效益。正如预期的那样,国家合作伙伴和研究合作伙伴之间的优先事项存在差异。为实现 2030 年区域消除疟疾的目标,应优先收集解决这些问题的证据。
更新日期:2021-01-12
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