This work continues a series of studies devoted to complex formation of ions of biogenic metals with the flavonoid dihydroquercetin (DHQ). The interaction of Со²⁺ ions with DHQ in aqueous solutions has been investigated. It has been found that, at different pH of a solution, complex compounds (CC) with different stoichiometry are formed; a variation of the pH value of a solution from 6.0 to 7.0 results in the formation of compounds (1)–(3) with the metal : flavonoid ligand ratio (Met : L) from 1 : 2 at рН 6.0 (1), through 2 : 3 at pH 6.4–6.7 (2), to 1 : 1 at рН 6.8–7.0 (3). By using the thermogravimetric method and the data of the elemental analysis, the most probable composition of the compounds with the determination of the amount of bound water has been proposed: [CoL₂(H₂O)₄] for (1), [Co₂L₃(ОН)(H₂O)₄] for (2), and [CoL(ОН)(H₂O)₂] for (3). Conditions for the optimization of product yield in the complexation reaction of Со²⁺ ions with DHQ in an aqueous solution have been determined for compound (2): the рН value of solution 6.7; the reaction time 15 min; the temperature of the reaction solution 90°С; the molar ratio of the initial reagents DHQ : Со²⁺ 1 : 1.5; the initial concentration of DHQ 0.020 mol/L and that of Со²⁺ 0.030 mol/L; and the use of CoSO₄ ⋅ 7H₂O as a source of cobalt ions. The yield of the product is 81.8%.

这项工作继续进行了一系列研究，这些研究致力于与类黄酮二氢槲皮素（DHQ）形成生物金属离子。已经研究了Со2 ⁺离子与DHQ在水溶液中的相互作用。已经发现，在溶液的不同pH下，会形成具有不同化学计量的复合化合物（CC）。溶液的pH值从6.0变为7.0会导致化合物（1）-（3）形成，其中金属：类黄酮配体比（Met：L）在рН6.0（1）时为1：2。2：3在pH 6.4-6.7（2），以1：1的在рН6.8-7.0（3）。通过使用热重分析法和元素分析数据，提出了测定结合水量最可能的化合物组成：[ 1 ]的[CoL ₂（H ₂ O）₄ ] ，[Co ₂大号₃（ОН）（H ₂ O）₄ ]对于（2），和[COL（ОН）（H ₂ O）₂ ]为（3）。已确定化合物（2）中²⁺离子与DHQ在水溶液中络合反应中优化产物收率的条件）：解6.7的рН值；反应时间15分钟；反应溶液温度90°С; 初始试剂DHQ的摩尔比：Со2 ⁺ 1：1.5; DHQ的初始浓度为0.020 mol / L，Со2 ⁺的初始浓度为0.030 mol / L；和使用COSO的₄ ⋅7H ₂ O为钴离子的来源。产品的产率为81.8％。