The “Undetectable = Untransmittable” campaign indicates that persons living with Human Immunodeficiency Virus (HIV) who maintain a suppressed viral load cannot sexually transmit the virus. However, there is little knowledge of the percent of individuals at a population level who sustain viral suppression long term. The aims of this study were to: (1) establish a baseline of persons living with diagnosed HIV who resided in New York and had consecutive suppressed viral load tests; (2) describe the risk of virologic failure among those who were consecutively suppressed; and (3) gain an understanding of the length of time between consecutive viral suppression to virologic failure. A total of 102,339 New Yorkers aged 13–90 years were living with diagnosed HIV at the beginning of 2012; 47.9% were consecutively suppressed (last two HIV viral load test results from 2010–2011 that were < 420 days apart and < 200 copies/mL). Of consecutively suppressed individuals, 54.3% maintained viral suppression for the entire study period and 33.6% experienced virologic failure during the study period. Among persons who experienced virologic failure, 82.6% did so six or more months after being consecutively suppressed. Our findings support the need for ongoing viral load monitoring, adherence support, and ongoing risk reduction messaging to prevent forward HIV transmission.

“无法检测 = 无法传播”运动表明，人类免疫缺陷病毒 (HIV) 感染者如果病毒载量保持在较低水平，则无法通过性行为传播该病毒。然而，对于人口水平上长期维持病毒抑制的个体百分比知之甚少。本研究的目的是：(1) 建立居住在纽约并连续进行抑制病毒载量测试的已确诊 HIV 感染者的基线；(2) 描述连续抑制的病毒学失败的风险；(3) 了解连续病毒抑制到病毒学失败之间的时间长度。2012 年初，共有 102,339 名 13-90 岁的纽约人感染了 HIV；47. 9% 被连续抑制（2010-2011 年的最后两次 HIV 病毒载量测试结果，间隔 < 420 天且 < 200 拷贝/mL）。在连续被抑制的个体中，54.3% 在整个研究期间保持病毒抑制，33.6% 在研究期间经历病毒学失败。在经历过病毒学失败的人中，82.6% 的人是在连续抑制六个月或更长时间后这样做的。我们的研究结果支持需要持续的病毒载量监测、依从性支持和持续的风险降低信息，以防止 HIV 向前传播。在经历过病毒学失败的人中，82.6% 的人是在连续抑制六个月或更长时间后这样做的。我们的研究结果支持需要持续的病毒载量监测、依从性支持和持续的风险降低信息，以防止 HIV 向前传播。在经历过病毒学失败的人中，82.6% 的人是在连续抑制六个月或更长时间后这样做的。我们的研究结果支持需要持续的病毒载量监测、依从性支持和持续的风险降低信息，以防止 HIV 向前传播。