Pre-exposure prophylaxis (PrEP) represents a viable HIV prevention tool for black men who have sex with men (BMSM). However, aggregated evidence regarding the presentations and determinants of the PrEP continuum (e.g., awareness, willingness, intention, uptake and adherence) remains absent to empirically inform future intervention efforts. We meta-analytically summarized the prevalence and qualitatively synthesized key barriers/facilitators of the stages of the PrEP continuum among a pooled sample of 42,870 BMSM aggregated from 56 published studies. Our random-effect models indicated a pooled prevalence of PrEP awareness (50.8%, 95% CI: 43.6–58.0%, willingness/intention (58.2%, 95% CI: 52.0–68.1%) and uptake (15.5%, 95% CI: 12.8–18.2%). Qualitative summary revealed that perception of HIV risk, intersectional/PrEP-related stigma and medical mistrust were among the most quoted factors that influence PrEP use. BMSM remain underrepresented in key stages of the PrEP continuum. Futures interventions are continuously needed to target multilevel barriers/facilitators to enhance the PrEP continuum among BMSM.

暴露前预防（PrEP）是一种可行的艾滋病预防工具，适用于与男性发生性关系的黑人（BMSM）。但是，仍缺乏有关PrEP连续体的表述和决定因素（例如意识，意愿，意图，摄取和坚持）的汇总证据，无法从经验上为未来的干预工作提供信息。我们通过荟萃分析总结了从56项已发表的研究汇总的42,870个BMSM样本中PrEP连续谱阶段的患病率和定性合成的关键障碍/促进因子。我们的随机效应模型表明，PrEP意识的综合患病率（50.8％，95％CI：43.6–58.0％，意愿/意图（58.2％，95％CI：52.0–68.1％）和摄取（15.5％，95％CI） ：12.8–18.2％）。定性摘要显示，您对HIV风险的感知，交叉/ PrEP相关的污名和医学上的不信任感是影响PrEP使用的最引证因素。在PrEP连续体的关键阶段，BMSM的代表性仍然不足。不断需要期货干预措施来针对多级障碍/促进者，以增强BMSM之间的PrEP连续性。