Dfam is an open access database of repetitive DNA families, sequence models, and genome annotations. The 3.0–3.3 releases of Dfam ( https://dfam.org ) represent an evolution from a proof-of-principle collection of transposable element families in model organisms into a community resource for a broad range of species, and for both curated and uncurated datasets. In addition, releases since Dfam 3.0 provide auxiliary consensus sequence models, transposable element protein alignments, and a formalized classification system to support the growing diversity of organisms represented in the resource. The latest release includes 266,740 new de novo generated transposable element families from 336 species contributed by the EBI. This expansion demonstrates the utility of many of Dfam’s new features and provides insight into the long term challenges ahead for improving de novo generated transposable element datasets.

中文翻译：

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转座因子家族、序列模型和基因组注释的 Dfam 社区资源

Dfam 是一个包含重复 DNA 家族、序列模型和基因组注释的开放存取数据库。Dfam 的 3.0-3.3 版本 (https://dfam.org) 代表了从模式生物中可转座元素家族的原理验证集合演变为广泛物种的群落资源，包括策划和未经整理的数据集。此外，自 Dfam 3.0 以来的版本提供了辅助的共有序列模型、转座因子蛋白质比对和正式的分类系统，以支持资源中代表的生物体不断增长的多样性。最新版本包括来自 EBI 贡献的 336 个物种的 266,740 个新的从头生成的转座因子家族。