Molecular genetic and structural studies have revealed the mechanisms of fundamental components of key auxin regulatory pathways consisting of auxin biosynthesis, transport, and signaling. Chemical biology methods applied in auxin research have been greatly expanded through the understanding of auxin regulatory pathways. Many small-molecule modulators of auxin metabolism, transport, and signaling have been generated on the basis of the outcomes of genetic and structural studies on auxin regulatory pathways. These chemical modulators are now widely used as essential tools for dissecting auxin biology in diverse plants. This review covers the structures, primary targets, modes of action, and applications of chemical tools in auxin biosynthesis, transport, and signaling.

中文翻译：

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生长素研究中的化学生物学

分子遗传学和结构研究揭示了由生长素生物合成、运输和信号转导组成的关键生长素调控途径的基本成分的机制。通过对生长素调控途径的理解，在生长素研究中应用的化学生物学方法得到了极大的扩展。许多生长素代谢、运输和信号转导的小分子调节剂是根据生长素调节途径的遗传和结构研究结果产生的。这些化学调节剂现在被广泛用作剖析不同植物中生长素生物学的重要工具。这篇综述涵盖了化学工具在生长素生物合成、运输和信号传导中的结构、主要目标、作用模式和应用。