In recent years, polyetheretherketone (PEEK) has been increasingly employed as an implant material in clinical applications. Although PEEK is biocompatible, chemically stable, and radiolucent and has an elastic modulus similar to that of natural bone, it suffers from poor integration with surrounding bone tissue after implantation. To improve the bioactivity of PEEK, numerous strategies for functionalizing the PEEK surface and changing the PEEK structure have been proposed. Inspired by the components, structure, and function of bone tissue, this review discusses strategies to enhance the biocompatibility of PEEK implants and provides direction for fabricating multifunctional implants in the future.

中文翻译：

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用于骨组织工程的 PEEK 植入物的仿生改良

近年来，聚醚醚酮（PEEK）作为植入材料越来越多地应用于临床。尽管PEEK具有生物相容性、化学稳定性和射线可透过性，并且具有与天然骨相似的弹性模量，但其在植入后与周围骨组织的融合性较差。为了提高 PEEK 的生物活性，人们提出了多种功能化 PEEK 表面和改变 PEEK 结构的策略。受骨组织的成分、结构和功能的启发，本综述讨论了增强 PEEK 植入物生物相容性的策略，并为未来制造多功能植入物提供了方向。