Although the influenza vaccine is widely recognized as an effective preventive measure, influenza vaccination rates among U.S. adults remain low. Moreover, influenza-related respiratory illnesses may increase the risk of adverse outcomes of COVID-19. Thus, this study examines the mechanisms involved in influenza vaccination uptake. Specifically, this study investigates how health information sources are associated with perceived vaccine efficacy and safety, which, in turn, associated with influenza vaccine uptake. Analyzing cross-sectional survey data from a national U.S. adult sample (N = 19,420), mediation analyses were conducted. Results revealed that considering vaccine efficacy, health information seekers who assigned more value to medical professionals, medical journals, and newspaper articles were more likely to perceive a vaccine as effective, thus being more likely to receive the influenza vaccine. By contrast, individuals who placed more value in social media were less likely to perceive vaccine efficacy, and, in turn, were less likely to get the influenza vaccine. Turning to vaccine safety, the value ascribed to medical professionals was positively associated with vaccine safety, which, in turn, related to influenza vaccine uptake. By contrast, social media, family or friends, and promotions were negatively associated with vaccine safety, and then influenza vaccine uptake.

尽管人们普遍认为流感疫苗是一种有效的预防措施，但美国成年人中的流感疫苗接种率仍然很低。此外，与流感有关的呼吸道疾病可能会增加COVID-19不良后果的风险。因此，本研究检查了流感疫苗吸收的机制。具体而言，本研究调查了健康信息源如何与感知的疫苗功效和安全性相关联，而后者又与流感疫苗的摄取相关联。分析来自美国成人样本的横断面调查数据（N= 19,420），进行了调解分析。结果表明，考虑到疫苗的功效，为医学专业人士，医学期刊和报纸文章赋予更多价值的健康信息搜寻者更有可能认为疫苗有效，因此更有可能接受流感疫苗。相比之下，在社交媒体上拥有更多价值的人则不太可能意识到疫苗的功效，因此，获得流感疫苗的可能性也较小。关于疫苗安全性，医务人员的价值与疫苗安全性正相关，而疫苗安全性又与流感疫苗的摄取有关。相比之下，社交媒体，家人或朋友以及促销活动与疫苗安全性，然后与流感疫苗的摄入量负相关。