The 2019 published National Institute for Health and Care Excellence abortion care guidance (NG140) recommends that antibiotic prophylaxis is offered to women who are having a surgical abortion and, when using doxycycline, a 100 mg two times a day for 3 days should be considered. The rationale to the recommendation states ‘a three day course because this may be as effective and adherence is likely to be better with a shorter outcome’. This is a shorter duration than that presented as part of the consultation. Originally, ‘the committee agreed that 7 days of doxycycline should be considered as it would be sufficient to treat sexually transmitted infections (STIs), if present. Further, there was expert knowledge that there is no evidence of increased antimicrobial resistance (AMR) with 7 days, compared with 3 days, of treatment. This is also consistent with the UK national recommendations for treating chlamydia’.1 The …

中文翻译：

---

新的NICE流产护理指南：使用抗生素意味着什么？

2019年发布的美国国家健康与护理卓越研究所堕胎护理指南（NG140）建议为手术流产的妇女提供抗生素预防措施，并且在使用强力霉素时，应考虑每天两次100毫克，共3天。该建议的理由是“为期三天的课程，因为这可能是有效的，并且依从时间越短越可能会更好”。这比咨询中提出的期限短。最初，“委员会同意应考虑使用强力霉素7天，因为它足以治疗性传播感染（STI）（如果存在的话）。此外，有专家知识表明，没有证据表明治疗3天后7天的抗药性增加（AMR）。