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Novel tissue interactions support the evolution of placentation
Journal of Morphology ( IF 1.5 ) Pub Date : 2021-01-18 , DOI: 10.1002/jmor.21322
Oliver W Griffith 1
Affiliation  

Organ development occurs through the coordinated interaction of distinct tissue types. So, a question at the core of understanding the evolution of new organs is, how do new tissue-tissue signalling networks arise? The placenta is a great model for understanding the evolution of new organs, because placentas have evolved repeatedly, evolved relatively recently in some lineages, and exhibit intermediate forms in extant clades. Placentas, like other organs, form from the interaction of two distinct tissues, one maternal and one fetal. If each of these tissues produces signals that can be received by the other, then the apposition of these tissues is likely to result in new signalling dynamics that can be used as a scaffold to support placenta development. Using published data and examples, in this review I demonstrate that placentas are derived from hormonally active organs, that considerable signalling potential exists between maternal and fetal tissues in egg-laying vertebrates, that this signalling potential is conserved through the oviparity-viviparity transition, and that consequences of these interactions form the basis of derived aspects of placentation including embryo implantation. I argue that the interaction of placental tissues, is not merely a consequence of placenta formation, but that novel interactions form the basis of new placental regulatory networks, functions, and patterning mechanisms. This article is protected by copyright. All rights reserved.

中文翻译:

新的组织相互作用支持胎盘的进化

器官发育是通过不同组织类型的协调相互作用发生的。因此,理解新器官进化的核心问题是,新的组织-组织信号网络是如何产生的?胎盘是理解新器官进化的一个很好的模型,因为胎盘反复进化,在一些谱系中相对较新进化,并在现存的进化枝中表现出中间形式。胎盘与其他器官一样,由两种不同组织相互作用形成,一种是母体,一种是胎儿。如果这些组织中的每一个都产生可以被另一个接收到的信号,那么这些组织的并置很可能会产生新的信号动力学,可以用作支持胎盘发育的支架。使用已发布的数据和示例,在这篇综述中,我证明胎盘来自激素活性器官,产卵脊椎动物的母体和胎儿组织之间存在相当大的信号传导潜力,这种信号传导潜力通过卵生-胎生过渡而保守,并且这些相互作用的结果形成胎盘的衍生方面的基础,包括胚胎植入。我认为胎盘组织的相互作用不仅是胎盘形成的结果,而且新的相互作用形成了新的胎盘调节网络、功能和模式机制的基础。本文受版权保护。版权所有。这种信号传导潜力是通过卵生-胎生过渡而保守的,这些相互作用的结果构成了胎盘包括胚胎植入在内的衍生方面的基础。我认为胎盘组织的相互作用不仅是胎盘形成的结果,而且新的相互作用形成了新的胎盘调节网络、功能和模式机制的基础。本文受版权保护。版权所有。这种信号传导潜力是通过卵生-胎生过渡而保守的,这些相互作用的结果构成了胎盘包括胚胎植入在内的衍生方面的基础。我认为胎盘组织的相互作用不仅是胎盘形成的结果,而且新的相互作用形成了新的胎盘调节网络、功能和模式机制的基础。本文受版权保护。版权所有。功能和模式化机制。本文受版权保护。版权所有。功能和模式化机制。本文受版权保护。版权所有。
更新日期:2021-01-18
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