Liquid nonbeverage alcohol products including flavors/flavorings, dietary supplements, medicines, etc. can be complex mixtures of flavor chemicals, adjuvants, and solvents. Ethanol and propylene glycol (PG) are common solvents used in the manufacture of nonbeverage alcohol products and the quantification of these analytes is important for both regulatory and quality control purposes. Presented here is a simple and robust gas chromatography-flame ionization detector (GC-FID) method which simultaneously quantifies ethanol and PG in liquid nonbeverage alcohol samples. The linear range is 0.4–95% v/v for ethanol and 1–99% v/v for PG with r 2 of > 0.999. The limit of detection for ethanol was 0.025% v/v and for PG was 0.05% v/v. The limit of quantification was calculated to be 0.075% v/v for ethanol and 0.15% v/v for PG. The method reproducibility was < 2.9%-RSD and < 3.2%-RSD for ethanol and PG, respectively. Spike recoveries for various matrices tested were between 98 and 107% at three different spike concentrations.

中文翻译：

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使用气相色谱火焰电离检测同时定量非饮料酒精产品中的乙醇和丙二醇

液体非饮料酒精产品包括香精/调味剂、膳食补充剂、药物等，可能是香精、佐剂和溶剂的复杂混合物。乙醇和丙二醇 (PG) 是生产非饮料酒精产品的常用溶剂，这些分析物的定量对于监管和质量控制都很重要。这里介绍的是一种简单而稳定的气相色谱-火焰离子化检测器 (GC-FID) 方法，该方法可同时量化液体非饮料酒精样品中的乙醇和 PG。乙醇的线性范围为 0.4–95% v/v，PG 的线性范围为 1–99% v/v，r 2 > 0.999。乙醇的检测限为 0.025% v/v，PG 的检测限为 0.05% v/v。计算的定量限为乙醇的 0.075% v/v 和 PG 的 0.15% v/v。乙醇和 PG 的方法重现性分别为 < 2.9%-RSD 和 < 3.2%-RSD。在三种不同的加标浓度下，测试的各种基质的加标回收率在 98% 到 107% 之间。