The effects of alginate oligosaccharides (AOs) on the growth performance and non-specific immunity of juvenile grass carp (Ctenopharyngodon idella) were investigated by performing a 60-day feeding trial. Four trial diets were formulated and supplemented with different doses of AOs (0, 100, 200 and 400 mg/kg). Triplicate groups of grass carp were fed with one of the diets twice daily. The grass carps fed with diets containing an appropriate dose of AOs for 60 days exhibited higher survival rates; body weight gains; specific growth rates; resistance to Aeromonas hydrophila; superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase activities; and serum total protein, lysozyme, alkaline phosphatase, complement C3, complement C4 and interleukin-10 expression levels and lower feed conversion ratios and malondialdehyde, alanine aminotransferase, aspartate aminotransferase, IL-1β expression, IL-8 expression and tumor necrosis factor-α expression levels than the control group (p < 0.05). Based on the effects of AOs on growth performance and survival percent, the optimum dose of AOs was 200 mg/kg. Results indicate that AOs as a dietary supplement enhances the growth performance and non-specific immunity of grass carps and their resistance to diseases.

通过进行为期 60 天的饲养试验，研究了海藻寡糖 (AOs) 对草鱼幼鱼 ( Ctenopharyngodon idella ) 生长性能和非特异性免疫的影响。配制了四种试验日粮，并添加了不同剂量的 AO（0、100、200 和 400 mg/kg）。每天两次用其中一种饲料喂养三组草鱼。饲喂含有适当剂量AOs饲料60天的草鱼表现出较高的成活率；体重增加；特定增长率；对嗜水气单胞菌的抗性; 超氧化物歧化酶、过氧化氢酶、谷胱甘肽过氧化物酶和谷胱甘肽还原酶活性；和血清总蛋白、溶菌酶、碱性磷酸酶、补体 C3、补体 C4 和白细胞介素 10 表达水平以及较低的饲料转化率和丙二醛、丙氨酸氨基转移酶、天冬氨酸氨基转移酶、IL-1β 表达、IL-8 表达和肿瘤坏死因子-α表达水平高于对照组（p  < 0.05）。基于 AOs 对生长性能和存活百分比的影响，AOs 的最佳剂量为 200 mg/kg。结果表明，AOs作为膳食补充剂可增强草鱼的生长性能和非特异性免疫力及其对疾病的抵抗力。