The Coronavirus Disease 2019 (COVID-19) epidemic has unprecedently affected many aspects of people’s lives including their health. This study examined the mediating effect of COVID-19 coping strategies on the relationship between COVID-19 anxiety and general health. Participants (70% females) included 4624 adults (M_age = 30.29 ± 10.97 years) collected through an online survey using a convenience sampling approach. Exploratory and confirmatory factor analyses yielded a one-factor structure for the COVID-19 Anxiety Scale (CFI = .98, TLI = .96, SRMR = .02, RMSEA = .09), COVID-19 Coping Scale (CFI = .97, TLI = .97, SRMR = .03, RMSEA = .12), and General Health Scale (CFI = .99, TLI = .97, SRMR = .01, RMSEA = .04) which were developed for the purpose of this study and exhibited satisfactory reliability. Findings showed that COVID-19 anxiety was negatively related with COVID-19 coping and general health. COVID-19 coping had a positive relationship with general health. Hierarchical multiple regression analyses revealed that COVID-19 coping partially mediated the relationship between COVID-19 anxiety and general health. These findings shed more light on the mechanism underlying between COVID-19 anxiety and health. The findings are important for tailoring and implementing coping-based intervention strategies to reduce the impact of COVID-19 anxiety on general health.

2019 年冠状病毒病 (COVID-19) 流行病前所未有地影响了人们生活的许多方面，包括他们的健康。本研究检验了 COVID-19 应对策略对 COVID-19 焦虑与总体健康之间关系的中介作用。参与者（70% 女性）包括 4624 名成年人（M_年龄 = 30.29 ± 10.97 年）通过使用方便抽样方法的在线调查收集。探索性和验证性因素分析得出了 COVID-19 焦虑量表 (CFI = .98, TLI = .96, SRMR = .02, RMSEA = .09)、COVID-19 应对量表 (CFI = .97) 的单因素结构, TLI = .97, SRMR = .03, RMSEA = .12)，以及为此目的开发的一般健康量表 (CFI = .99, TLI = .97, SRMR = .01, RMSEA = .04)研究并表现出令人满意的可靠性。研究结果表明，COVID-19 焦虑与 COVID-19 应对和总体健康呈负相关。COVID-19 应对与总体健康呈正相关。分层多元回归分析显示，COVID-19 应对部分调节了 COVID-19 焦虑与一般健康之间的关系。这些发现进一步阐明了 COVID-19 焦虑与健康之间的潜在机制。这些发现对于定制和实施基于应对的干预策略以减少 COVID-19 焦虑对整体健康的影响非常重要。