Enantioselective desymmetrization of prochiral cyclohexadienones and kinetic resolution of racemic cyclohexadienones are powerful strategies for the construction of enantiomerically enriched cyclohexanone-containing molecules, which are frequently found in bioactive natural products. Significant progress has been made in this research area in recent years, especially in transition metal catalyzed intramolecular enantioselective desymmetrization and asymmetric kinetic resolution aspects. This review provides an overview of the recent advances in this field, and briefly explains the remaining challenges and future perspectives.

中文翻译：

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非手性环己二酮不对称转化的最新进展

前手性环己二酮的对映选择性去对称化和外消旋环己二酮的动力学拆分是构建对映体富集的含有环己酮的分子的有力策略，其经常在生物活性天然产物中发现。近年来，在该研究领域已经取得了重大进展，尤其是在过渡金属催化的分子内对映选择性脱对称和不对称动力学拆分方面。这篇综述概述了该领域的最新进展，并简要解释了剩余的挑战和未来的前景。