The transition from episodic migraine to chronic migraine, migraine chronification, is usually a gradual process, which involves multiple risk factors. To date, studies of the genetic risk factors for chronic migraine have focused primarily on candidate‐gene approaches using healthy individuals as controls.

中文翻译：

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慢性偏头痛：遗传还是环境？

从发作性偏头痛到慢性偏头痛（即偏头痛慢性化）的转变通常是一个渐进的过程，涉及多种危险因素。迄今为止，慢性偏头痛遗传风险因素的研究主要集中于使用健康个体作为对照的候选基因方法。