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Phagocytosis: Sweet Repulsions via the Glycocalyx
Current Biology ( IF 9.2 ) Pub Date : 2021-01-11 , DOI: 10.1016/j.cub.2020.10.066 Sophia Maschalidi 1 , Kodi S Ravichandran 2
中文翻译:
吞噬作用:通过糖萼的甜味排斥
更新日期:2021-01-11
Current Biology ( IF 9.2 ) Pub Date : 2021-01-11 , DOI: 10.1016/j.cub.2020.10.066 Sophia Maschalidi 1 , Kodi S Ravichandran 2
Affiliation
New work shows that the glycocalyx meshwork on the surface of macrophages prevents phagocytic receptors from binding their ligands by two means — electrostatic charge and steric hindrance. Components of this barrier are present on pathogenic and malignant targets that elude phagocytosis.
中文翻译:
吞噬作用:通过糖萼的甜味排斥
新的研究表明,巨噬细胞表面的糖萼网状结构通过两种方式阻止吞噬受体与配体结合:静电荷和位阻。该屏障的成分存在于致吞噬作用的致病和恶性靶标上。