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Gluing Proteins for Targeted Degradation
Cancer Cell ( IF 50.3 ) Pub Date : 2021-01-11 , DOI: 10.1016/j.ccell.2020.12.020
Mikihiko Naito 1 , Shigeo Murata 2
Affiliation  

Targeted protein degradation is an emerging technology for drug development. An article published in Nature reported a novel mechanism of targeted protein degradation triggered by small-molecule-induced polymerization of the oncogenic transcription factor BCL6.



中文翻译:

粘合蛋白质以实现目标降解

靶向蛋白质降解是药物开发的新兴技术。在《自然》杂志上发表的一篇文章报道了由小分子诱导的致癌转录因子BCL6聚合引发的靶向蛋白质降解的新机制。

更新日期:2021-01-11
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