Abstract

The catalytic activity of C,N-chelate diaminocarbene palladium(II) complexes containing a 3,4-diaryl-1H-pyrrol-2,5-diimine fragment in a copper-free Sonogashira reaction was studied. Reactions catalyzed by C,N-chelate diaminocarbene palladium(II) complexes do not require preliminary degassing, since such catalysts are air- and moisture-stable. In this work, comparative analysis of the catalytic activity of two types of C,N-chelate diaminocarbene complexes containing, along with the diaminocarbene ligand, isonitrile and chloride or two chloride ligands in the inner coordination sphere has been carried out. The steric and electronic effects of the substituents in the catalyst on the reaction yield has been studied.

中文翻译：

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C，N-螯合二氨基碳烯钯（II）配合物的结构对其在Sonogashira反应中催化活性的影响

摘要

研究了在无铜Sonogashira反应中含3,4-二芳基-1 H-吡咯-2,5-二亚胺片段的C，N-螯合二氨基碳烯钯（II）配合物的催化活性。由C，N-螯合物二氨基碳烯钯（II）配合物催化的反应不需要预先脱气，因为这种催化剂是空气和水分稳定的。在这项工作中，对两种类型的C，N的催化活性进行比较分析-已经在内部配位球中制备了含有二氨基卡宾配体，异腈和氯化物或两个氯化物配体的-螯合物二氨基卡宾配合物。研究了催化剂中取代基对反应产率的空间和电子效应。