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On the potential role of lateral connectivity in retinal anticipation
The Journal of Mathematical Neuroscience ( IF 2.3 ) Pub Date : 2021-01-09 , DOI: 10.1186/s13408-020-00101-z
Selma Souihel , Bruno Cessac

We analyse the potential effects of lateral connectivity (amacrine cells and gap junctions) on motion anticipation in the retina. Our main result is that lateral connectivity can—under conditions analysed in the paper—trigger a wave of activity enhancing the anticipation mechanism provided by local gain control (Berry et al. in Nature 398(6725):334–338, 1999; Chen et al. in J. Neurosci. 33(1):120–132, 2013). We illustrate these predictions by two examples studied in the experimental literature: differential motion sensitive cells (Baccus and Meister in Neuron 36(5):909–919, 2002) and direction sensitive cells where direction sensitivity is inherited from asymmetry in gap junctions connectivity (Trenholm et al. in Nat. Neurosci. 16:154–156, 2013). We finally present reconstructions of retinal responses to 2D visual inputs to assess the ability of our model to anticipate motion in the case of three different 2D stimuli.

中文翻译:

侧向连接在视网膜预测中的潜在作用

我们分析了对视网膜运动预期中的横向连接(amacrine细胞和间隙连接)的潜在影响。我们的主要结果是,在本文分析的条件下,横向连通性可以触发一波活动,从而增强局部增益控制所提供的预期机制(Berry等,Nature 398(6725):334-338,1999; Chen等) et al。in J. Neurosci。33(1):120-132,2013)。我们通过在实验文献中研究的两个例子来说明这些预测:差分运动敏感细胞(Baccus和Meister在Neuron 36(5):909-919,2002)和方向敏感细胞中,方向敏感性是从间隙连接连通性的不对称继承的( Trenholm et al。in Nat。Neurosci。16:154–156,2013)。
更新日期:2021-01-10
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