CCS Chemistry ( IF 11.2 ) Pub Date : 2021-01-08 , DOI: 10.31635/ccschem.021.202000596 Ming Chen 1 , Xucai Wang 1 , Zhi-Hui Ren 1 , Zheng-Hui Guan 1
Herein, we report a novel palladium (Pd)-catalyzed asymmetric domino Heck/carbocyclization/Suzuki reaction of N-(2-bromoaryl)-2-naphthylacrylamides. The reaction involves a novel and enantioselective dearomative 1,2-insertion of the naphthalene group, thus providing a unique dearomatization strategy of nonactivated naphthalenes. A new phosphoramidite ligand
中文翻译:
钯催化的不对称多米诺骨节/碳环化/铃木反应:非活化萘的脱芳香化作用
在这里,我们报告了新型钯(Pd)催化的N-(2-溴芳基)-2-萘丙烯酰胺的不对称多米诺Heck /碳环化/ Suzuki反应。该反应涉及萘基团的新颖和对映选择性脱芳香基的1,2-插入,因此提供了非活化萘的独特的脱芳香化策略。一种新的亚磷酰胺配体