Two derivatives of lysine were synthesized by acylating the Nα with dodecanoic acid starting from commercial precursors in which the Nε was already acylated by the benzoyloxycarbonyl or o‐chloro‐benzoyloxycarbonyl group. Both derivatives self‐assembled in dimethylsulfoxide/water mixtures (above 40% v/v water) leading to solid‐like formulations. The rheological properties were studied as a function of gelator concentration and solvent composition. From stress sweep experiments it was assumed that the gels consisted of jammed suspensions of mesoscopic clusters formed by self‐assembly processes similar to those at the origin of crystallization. The temporal variation of storage and loss moduli was monitored immediately after mixing over times between 20 and 120 min using isothermal oscillatory rheological experiments. Experimental curves were satisfactorily depicted using previously reported semi‐empirical equations. Both transient evolution and stationary values were consistent with the representation of gels as resulting from the formation, one‐dimensional growth and dynamic arrest of fractal clusters (with fractal dimension between 1.6 and 2.0). The presence of a chlorine atom within the aromatic ring of one of the lysine derivatives induced a significant increase of the gelation time scale and a decrease of rheological moduli. © 2021 Society of Chemical Industry

中文翻译：

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赖氨酸衍生物在水/二甲亚砜混合物中的超分子物理凝胶的流变学研究

赖氨酸的两种衍生物是通过十二烷酸酰化Nα合成的，其起始原料是商业化的前体，其中Nε已被苯甲酰氧羰基或邻苯二甲酰化。氯-苯甲酰氧基羰基 两种衍生物在二甲亚砜/水混合物（v / v高于40％的水）中自组装，形成固体样。研究了流变性质随胶凝剂浓度和溶剂组成的变化。从应力扫描实验中，可以假定凝胶由介观团簇的堵塞悬浮液组成，这些团簇通过类似于结晶起点的自组装过程形成。使用等温振荡流变实验，在20到120分钟之间的混合时间后立即监测储能和损耗模量的时间变化。使用先前报道的半经验方程式令人满意地描绘了实验曲线。分形团簇的形成，一维生长和动态阻滞（分形维数在1.6和2.0之间）导致的瞬时演化和静态值均与凝胶的表示一致。赖氨酸衍生物之一的芳环内存在氯原子会导致凝胶时间尺度的显着增加和流变模量的降低。©2021化工协会