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Spatial population genomics of a recent mosquito invasion
Molecular Ecology ( IF 4.9 ) Pub Date : 2021-01-09 , DOI: 10.1111/mec.15792
Thomas L Schmidt 1 , Tom Swan 2, 3 , Jessica Chung 1, 4 , Stephan Karl 2, 5 , Samuel Demok 5 , Qiong Yang 1 , Matt A Field 2, 6 , Mutizwa Odwell Muzari 7 , Gerhard Ehlers 7 , Mathew Brugh 7 , Rodney Bellwood 7 , Peter Horne 7 , Thomas R Burkot 2 , Scott Ritchie 3, 8 , Ary A Hoffmann 1
Affiliation  

Population genomic approaches can characterize dispersal across a single generation through to many generations in the past, bridging the gap between individual movement and intergenerational gene flow. These approaches are particularly useful when investigating dispersal in recently altered systems, where they provide a way of inferring long‐distance dispersal between newly established populations and their interactions with existing populations. Human‐mediated biological invasions represent such altered systems which can be investigated with appropriate study designs and analyses. Here we apply temporally restricted sampling and a range of population genomic approaches to investigate dispersal in a 2004 invasion of Aedes albopictus (the Asian tiger mosquito) in the Torres Strait Islands (TSI) of Australia. We sampled mosquitoes from 13 TSI villages simultaneously and genotyped 373 mosquitoes at genome‐wide single nucleotide polymorphisms (SNPs): 331 from the TSI, 36 from Papua New Guinea (PNG) and four incursive mosquitoes detected in uninvaded regions. Within villages, spatial genetic structure varied substantially but overall displayed isolation by distance and a neighbourhood size of 232–577. Close kin dyads revealed recent movement between islands 31–203 km apart, and deep learning inferences showed incursive Ae. albopictus had travelled to uninvaded regions from both adjacent and nonadjacent islands. Private alleles and a co‐ancestry matrix indicated direct gene flow from PNG into nearby islands. Outlier analyses also detected four linked alleles introgressed from PNG, with the alleles surrounding 12 resistance‐associated cytochrome P450 genes. By treating dispersal as both an intergenerational process and a set of discrete events, we describe a highly interconnected invasive system.

中文翻译:

最近一次蚊子入侵的空间种群基因组学

种群基因组学方法可以表征过去一代到一代的扩散,弥合了个体运动与代际基因流之间的鸿沟。这些方法在调查最近更改的系统中的分散时特别有用,它们提供了一种方法来推断新建立的种群之间的长距离分散及其与现有种群的相互作用。人类介导的生物入侵代表了这种改变的系统,可以通过适当的研究设计和分析进行研究。在这里,我们应用时间限制采样和一系列种群基因组学方法来调查2004年白纹伊蚊入侵中的扩散(亚洲虎蚊)在澳大利亚的托雷斯海峡群岛(TSI)。我们同时采样了来自13个TSI村庄的蚊子,并在全基因组单核苷酸多态性(SNP)上对373种蚊子进行了基因分型:来自TSI的331种,来自巴布亚新几内亚(PNG)的36种,以及在未入侵地区发现的四种入侵蚊子。在村庄内,空间遗传结构变化很大,但总体上显示出距离和邻里大小(232-577)之间的隔离。亲密的亲缘关系揭示了最近的两岛之间相距31-203公里之间的运动,而深度学习推论则显示了侵入性Ae。白化病从相邻和不相邻的岛屿前往未入侵的地区。私人等位基因和祖先矩阵表明基因直接从PNG流入附近的岛屿。离群值分析还检测到从PNG渗入的四个连锁等位基因,这些等位基因围绕12个抗性相关的细胞色素P450基因。通过将传播视为代际过程和一系列离散事件,我们描述了高度相互联系的入侵系统。
更新日期:2021-02-24
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