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Epilepsy in the Hippocratic collection: Seizures and syndromes
Epilepsy & Behavior ( IF 2.6 ) Pub Date : 2021-02-01 , DOI: 10.1016/j.yebeh.2020.107704
William H. Theodore

Despite extensive scholarship, several questions on the view of seizures and epilepsy in the Hippocratic collection have not been answered. The book 'On the Sacred Disease' contains descriptions of focal and generalized tonic-clonic seizures, understands the stigma attached to epilepsy, its association with depression, and probably describes auras. Remarkably, the collection presents a physiologic theory of 'mental' disease. Other parts of the collection suggest recognition of syndromes such as childhood febrile seizures. Non-motor seizures are not clearly described. There may be a distinction between 'acute symptomatic' and recurrent seizures or 'epilepsy.' Analysis of the relative occurrence of terms related to 'epilepsy' or 'spasms' in an online text collection shows a significant difference: 'epilepsy' terms are more frequent when seizures are described alone, while 'spasm' terms are more frequent in the context of systemic diseases or injuries. This dichotomy suggests, in contrast to previous accounts, possible understanding of the distinction between 'idiopathic' and 'symptomatic' seizure disorders.

中文翻译:

希波克拉底收藏中的癫痫:癫痫发作和综合征

尽管有广泛的学术研究,但希波克拉底收藏中关于癫痫发作和癫痫的几个问题尚未得到解答。《论神圣的疾病》一书描述了局灶性和全身性强直阵挛性癫痫发作,了解了癫痫的耻辱感及其与抑郁症的关联,并可能描述了先兆。值得注意的是,该系列提出了“精神”疾病的生理学理论。该系列的其他部分表明可以识别儿童热性惊厥等综合征。没有明确描述非运动性癫痫发作。“急性症状性”和反复发作或“癫痫”之间可能存在区别。在线文本集合中与“癫痫”或“痉挛”相关的术语的相对出现率分析显示出显着差异:当单独描述癫痫发作时,“癫痫”术语更常见,而在全身性疾病或损伤的背景下,“痉挛”术语更常见。与之前的描述相反,这种二分法表明,可能理解“特发性”和“症状性”癫痫症之间的区别。
更新日期:2021-02-01
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