Calluna vulgaris (L.) Hull belonging to Ericaceae family occurs mostly at sour habitats in subalpine regions in Europe. The species is cultivated in many countries, but it is known as medicinal plant because of polyphenols and aucubin as main compounds. In this work, the polyphenolic, flavonoid, and tannin content, as well as the antimicrobial and antioxidant activity of the aerial part, were evaluated. In phytochemical analyses, methanol extract showed the highest phenolic and flavonoid content, followed by ethanol, methanol/water, and aqueous extracts. In antimicrobial tests, chloroform, ethyl acetate, butanol, and water extracts inhibited the growth of S. aureus and MRSA, while butanol and water fractions were effective against E. coli, and water extract for E. coli ESBL and K. pneumoniae ESBL. Water extract showed the most inhibitory effect for the tested 2 g-positive and 3 g-negative strains including both bactericidal and bacteriostatic activity. Data analysed by Pearson coefficient correlation showed positive correlation between polyphenol and flavonoid content. The determined antioxidant capacity of the herb ranged from 0.145 to 0.296 mg/mL. The results highlight the significance of the plant as possible antioxidant source and as an antimicrobial agent for further studies.

Calluna vulgaris (L.) Hull 属于杜鹃花科，主要生长在欧洲亚高山地区的酸性栖息地。该物种在许多国家都有栽培，但它以多酚和茄子为主要化合物而被称为药用植物。在这项工作中，评估了地上部分的多酚、类黄酮和单宁含量，以及抗微生物和抗氧化活性。在植物化学分析中，甲醇提取物的酚类和类黄酮含量最高，其次是乙醇、甲醇/水和水提取物。在抗菌测试中，氯仿、乙酸乙酯、丁醇和水提取物抑制金黄色葡萄球菌和MRSA的生长，而丁醇和水提取物对大肠杆菌有效，以及大肠杆菌ESBL 和肺炎克雷伯菌 ESBL的水提取物。水提取物对测试的 2 g 阳性和 3 g 阴性菌株显示出最大的抑制作用，包括杀菌和抑菌活性。通过皮尔逊系数相关分析的数据显示多酚和黄酮含量呈正相关。确定的草药的抗氧化能力范围为 0.145 至 0.296 mg/mL。结果突出了植物作为可能的抗氧化剂来源和作为进一步研究的抗菌剂的重要性。