Induced polyploidy serves as an efficient approach in extricating genetic potential of cells. During polyploidization, multiple sets of chromosomes are derived from the same organism resulting in the development of an autopolyploid. Alterations owing to artificially induced polyploidy level significantly influence internal homeostatic condition of resultant cells. Induced autopolyploidy transpires as a result of an increase in the size of genome without any change in elementary genetic material. Such autopolyploidy, artificially induced via application of antimitotic agents, brings about a lot of beneficial changes in plants, coupled with very few detrimental effects. Induced autopolyploids exhibit superior adaptability, endurance to biotic and abiotic stresses, longer reproductive period and enzyme diversity coupled with enhanced rate of photosynthesis and gene action in comparison to their diploid counterparts. However, reduced rate of transpiration and growth, delay in flowering are some of the demerits of autopolyploids. Inspite of these slight unfavourable outcomes, induced autopolyploidization has been utilized in an array of instances wherein genetic improvement of plant species is concerned, since this technique usually boosts the biomass of concerned economic parts of a plant. In other way, it is also evident that multiplication of genome bestows enhanced production of secondary metabolites, which has contributed to a significant commercial value addition especially for plants with medicinal importance, in particular. This review makes an attempt to explore the system and success of antimitotic agents vis-à-vis artificial autopolyploidization, interfered with the biosynthesis-cum-production of secondary metabolites having cutting-edge pharmaceutical importance.

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诱导同源多倍体——增强植物次生代谢物生物合成的有前景的方法：洞察

诱导多倍体是释放细胞遗传潜力的有效方法。在多倍体化过程中，多组染色体来自同一生物体，从而形成同源多倍体。由于人为诱导的多倍体水平的改变显着影响所得细胞的内部稳态条件。诱导的同源多倍体由于基因组大小的增加而发生，而基本遗传物质没有任何变化。这种通过应用抗有丝分裂剂人为诱导的同源多倍体给植物带来了许多有益的变化，而有害影响却很少。诱导的同源多倍体表现出优异的适应性，对生物和非生物胁迫的耐受性，与二倍体对应物相比，更长的繁殖期和酶的多样性，以及更高的光合作用和基因作用速率。然而，蒸腾和生长速度降低，开花延迟是同源多倍体的一些缺点。尽管有这些轻微的不利结果，诱导同源多倍体化已被用于植物物种遗传改良的一系列实例中，因为这种技术通常会提高植物相关经济部分的生物量。另一方面，很明显，基因组的增殖增强了次生代谢物的产量，这有助于显着增加商业价值，尤其是对于具有药用价值的植物而言。