PURPOSE We determined whether resilience factors such as self-efficacy, stress coping styles, and social support were differentially associated with health-related quality of life (HRQoL) in men and women with epilepsy after controlling for depression, anxiety, and daily-life stress. METHODS This was a cross-sectional study of 129 adults with epilepsy. The Quality of Life in Epilepsy Inventory-31 (QOLIE-31), Epilepsy Self-Efficacy Scale, Way of Stress Coping Checklist, Social Support Scale, Beck Depression Inventory (BDI), Beck Anxiety Inventory, and Daily Hassles Scale were used. Stepwise linear regression analyses were performed. RESULTS Except for medication effects, there were no gender differences in the QOLIE-31 and its subscales. The medication effects score was higher in men than in women after controlling for BDI scores. The BDI scores were independently associated with the QOLIE-31 score in men and women. Epilepsy self-efficacy was associated with the QOLIE-31 in men, whereas social support was associated with the QOLIE-31 in women. Coping strategies were associated with the QOLIE-31 in neither men nor women. Seizure frequency, daily-life stress, and anxiety were also negatively associated with the QOLIE-31, but only in men. The coefficients of determination were 0.637 and 0.587 in the men's and women's models, respectively. CONCLUSIONS The influence of self-efficacy and social support on HRQoL differed between men and women with epilepsy even after controlling for psychological distress. These findings could contribute to the development of successful gender-specific psychosocial interventions to improve HRQoL in men and women with epilepsy.

中文翻译：

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与癫痫患者健康相关生活质量恢复力相关因素的性别差异

目的 我们确定在控制抑郁、焦虑和日常生活压力后，自我效能感、压力应对方式和社会支持等弹性因素是否与癫痫男性和女性的健康相关生活质量 (HRQoL) 存在差异. 方法 这是一项对 129 名成人癫痫患者的横断面研究。使用癫痫生活质量量表-31 (QOLIE-31)、癫痫自我效能量表、压力应对方式清单、社会支持量表、贝克抑郁量表 (BDI)、贝克焦虑量表和日常麻烦量表。进行逐步线性回归分析。结果除药物作用外，QOLIE-31及其分量表均无性别差异。在控制 BDI 评分后，男性的药物作用评分高于女性。BDI 评分与男性和女性的 QOLIE-31 评分独立相关。癫痫自我效能与男性的 QOLIE-31 相关，而社会支持与女性的 QOLIE-31 相关。无论男性还是女性，应对策略都与 QOLIE-31 相关。癫痫发作频率、日常生活压力和焦虑也与 QOLIE-31 呈负相关，但仅限于男性。男性和女性模型的决定系数分别为 0.637 和 0.587。结论 即使在控制了心理困扰后，自我效能感和社会支持对 HRQoL 的影响在男性和女性癫痫患者之间也存在差异。这些发现可能有助于开发成功的针对特定性别的社会心理干预措施，以改善男性和女性癫痫患者的 HRQoL。