Alternaria solani is one of the most notorious fungal pathogens that causes the destructive early blight (EB) disease of tomato (Solanum lycopersicum L.). Direct application of pesticide is a perilous approach to control disease due to its residual effects, therefore manipulating crop nutrition is a holistic approach to mitigate EB disease by improving the resilience in plants against disease in the sustainable cropping system. Achieving this aim, the effects of plant nutrients viz., nitrogen, phosphorus, potassium (NPK), zinc (Zn), magnesium (Mg) and boron (B) were investigated in controlling early blight disease of tomato. Pathogen infestation camouflaged cell mechanism and disturbed the regulation of key player enzymes (SOD, CAT, POX, PPO and PAL) that weakened the plant immunity, therefore, the plants exhibited 100% disease incidence. Applied nutrients reduced the EB disease by effective interference that leads to the induction of resistance in a host against pathogens to a variable extent. Zn proved strong co-factor for the activation of defense-related enzymes that ultimately managed the EB disease from 60–75% and significantly improved the plant growth and physiological attributes by 30–80% with the significant Pearson correlation among defense-related enzymes and total phenolics. The rest of nutrients were not found to be effective in suppressing disease because the correlation among antioxidant enzymes probably did not facilitate intercellular communications to the desired level to boost up plant immune system.

Solnaria solani是最臭名昭著的真菌病原体之一，它引起番茄的破坏性早疫病（EB）病害（Solanum lycopersicumL.）。由于农药的残留效应，直接施用农药是控制病害的危险方法，因此，控制作物营养是通过提高植物在可持续种植系统中对疾病的适应力来减轻EB病害的整体方法。为了实现这一目标，研究了植物营养素，即氮，磷，钾（NPK），锌（Zn），镁（Mg）和硼（B）在控制番茄早疫病中的作用。病原体侵染伪装了细胞机制，干扰了削弱植物免疫力的关键球员酶（SOD，CAT，POX，PPO和PAL）的调控，因此，植物表现出100％的病害发生率。所施加的营养素通过有效的干预降低了EB疾病，从而有效地诱导了宿主对病原体的抗性。锌被证明是防御相关酶激活的强大辅助因子，最终控制了EB病的发病率从60％到75％，并显着改善了植物生长和生理特性30-80％，而防御相关酶和总酚。其余的营养物质未发现能有效抑制疾病，因为抗氧化酶之间的相关性可能无法促进细胞间通讯达到所需水平，从而无法增强植物的免疫系统。