Chlorothalonil (CTL), an organic biocide, was successfully incorporated into polylactic acid-co-polyethylene glycol (PLA-PEG) nanoparticles via nanoprecipitation method. The hydrodynamic particle size and CTL loading efficiency of synthesized CTL-PLA-PEG nanoparticles were 12.8 ± 0.2 nm and 65.9 ± 0.4%, respectively. Rubberwood (Hevea brasiliensis) samples were treated with 0.025% w/v aqueous suspension of nanoparticles by a vacuum pressure treatment. The studies showed that the pressure and duration needed could be reduced compared to the conventional condition without compromising the effectiveness of the treatment. Good treatability (42.3 ± 3.4 L m^− 3) and high chemical retention (8.5 ± 0.1 kg m^− 3) were achieved for the wood treated with CTL-PLA-PEG nanoparticles. Biological efficacy performance of the treated wood against subterranean termites (Coptotermes curvignathus), white-rot fungi (Trametes versicolor) and brown-rot fungi (Gloeophyllum trabeum) was evaluated. Weight loss of rubberwood treated with nanoparticles was reduced from 9.7 ± 0.3% to 3.6 ± 0.2% in termite test. In addition, CTL-PLA-PEG nanoparticles decreased the weight loss attributed to brown-rot fungi from 37.1 ± 0.1% to 11.4 ± 0.4%. As for study with white-rot fungi, weight loss of rubberwood treated with CTL-PLA-PEG nanoparticles decreased from 38.9 ± 1.0% to 19.2 ± 0.7%.

通过纳米沉淀法将有机杀虫剂氯噻酮（CTL）成功地掺入到聚乳酸-共-聚乙二醇（PLA-PEG）纳米颗粒中。合成的CTL-PLA-PEG纳米颗粒的流体动力学粒径和CTL装载效率分别为12.8±0.2 nm和65.9±0.4％。通过真空压力处理，用0.025％w / v的纳米颗粒水悬浮液处理橡胶木（巴西橡胶树）样品。研究表明，与常规情况相比，可以减少所需的压力和持续时间，而不会影响治疗的有效性。良好的可处理性（42.3±3.4 L m ^{− 3}）和高化学保留（8.5±0.1 kg m ^{− 3}对于用CTL-PLA-PEG纳米颗粒处理过的木材而言，可达到）。评价了处理过的木材对地下白蚁（Coptotermes curvignathus），白腐真菌（Trametes versicolor）和棕腐真菌（Gloeophyllum trabeum）的生物功效性能。在白蚁试验中，用纳米颗粒处理的橡胶木的重量损失从9.7±0.3％降低到3.6±0.2％。另外，CTL-PLA-PEG纳米颗粒将归因于褐腐真菌的体重减轻从37.1±0.1％降低到11.4±0.4％。对于白腐真菌的研究，用CTL-PLA-PEG纳米颗粒处理的橡胶木的重量减轻从38.9±1.0％降至19.2±0.7％。