Pericytes surround the endothelial cells in microvessels and play a distinct role in controlling vascular permeability and maturation. The loss of pericyte function is known to be associated with diabetic retinopathy and erectile dysfunction. This study aimed to establish a technique for the isolation of pericytes from the mouse urinary bladder and an in vitro model that mimics in vivo diabetic bladder dysfunction.

中文翻译：

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一种从小鼠膀胱中分离出周细胞的方法，用于研究糖尿病膀胱功能障碍。

周细胞围绕微血管中的内皮细胞，并在控制血管通透性和成熟中起独特作用。已知周细胞功能的丧失与糖尿病性视网膜病和勃起功能障碍有关。这项研究旨在建立一种从小鼠膀胱中分离周细胞的技术，以及一种模仿体内糖尿病性膀胱功能障碍的体外模型。