ABSTRACT

The aim of the study is to investigate the inflammation markers in bipolar affective disorder(BAD) patients who were involved in crime or did not involve in crime. It was aimed to evaluate the neutrophil/lymphocyte ratios (NLR), platelet/lymphocyte ratios (PLR), monocyte/lymphocyte ratios (MLR) and platelete distribution width (RDW) by comparing with controls and each other. 272 individuals were included in our study; patients diagnosed with BAD (100 committed a crime, 72 has no criminal history) in the patient group and 100 individuals in the control. The hemoglobin, hematocrit and PDW levels were found higher in the group involved in crime than the group not involved in crime as well as controls. Also, hemoglobin, hematocrit, WBC, RBC, PDW, neutrophil, monocyte values were found higher in the patients involved in crime than the patients not involved in crime. NLR, PLR and MLR were found low in both patient groups compared to controls. Based on our results; some inflammatory parameters were different in the patients involved in crime than the group not involved in crime and healthy controls. To generalize the findings of our study and to make them significant, prospective studies should be conducted with larger sample groups and people with different disorders.

摘要

本研究的目的是调查参与犯罪或未参与犯罪的双相情感障碍（BAD）患者的炎症标志物。目的是通过与对照和相互比较来评估中性粒细胞/淋巴细胞比率（NLR）、血小板/淋巴细胞比率（PLR）、单核细胞/淋巴细胞比率（MLR）和血小板分布宽度（RDW）。272 个人被纳入我们的研究；患者组中诊断为 BAD 的患者（100 人犯罪，72 人无犯罪史），对照组 100 人。发现参与犯罪组的血红蛋白、血细胞比容和 PDW 水平高于未参与犯罪组和对照组。此外，血红蛋白、血细胞比容、WBC、RBC、PDW、中性粒细胞、发现参与犯罪的患者的单核细胞值高于未参与犯罪的患者。与对照组相比，两个患者组的 NLR、PLR 和 MLR 均较低。基于我们的结果；参与犯罪的患者与未参与犯罪的组和健康对照组的一些炎症参数不同。为了概括我们的研究结果并使其具有重要意义，应该对更大的样本组和不同疾病的人群进行前瞻性研究。