Among various transition metal complexes, platinum(II) complexes are among one of the most extensively explored classes of metal complexes for supramolecular assembly, as their square‐planar molecular geometry allows axial interactions between adjacent complex molecules and access to the formation of supramolecular assemblies with the aid of noncovalent Pt(II)⋯Pt(II) interactions. In the presence of external stimuli, alkynylplatinum(II) polypyridine complexes can self‐assemble with alterations in their spectroscopic and luminescence properties. In light of their inherent advantages, including low‐energy photoexcitation, red to near‐infrared emission, large Stokes shifts, long phosphorescence lifetimes and high photostability, successful applications of alkynylplatinum(II) polypyridine complexes in the detection of biological analytes have been made possible. In this account, presented in part of the FACS Foundation Lecture, we introduce the basic concepts and our recent advances in the development of detection assays for various biomolecules based on luminescent alkynylplatinum(II) polypyridine complexes with selected examples.

中文翻译：

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发光炔基铂（II）聚吡啶配合物的超分子自组装及其生物学应用的最新进展

在各种过渡金属配合物中，铂（II）配合物是超分子组装中最广泛探索的金属配合物之一，因为它们的方平面分子几何形状允许相邻配合物分子之间发生轴向相互作用，并可以形成具有非共价Pt（II）⋯Pt（II）相互作用的帮助。在存在外部刺激的情况下，炔基铂（II）聚吡啶配合物可以自组装，但其光谱和发光特性也会发生变化。考虑到它们的固有优势，包括低能量的光激发，红色至近红外发射，大的斯托克斯频移，长的磷光寿命和高的光稳定性，炔基铂（II）聚吡啶配合物在生物分析物中的成功应用已成为可能。在此说明中，我们在FACS基础讲座的一部分中介绍了基本概念以及我们在开发基于发光炔基铂（II）聚吡啶复合物的各种生物分子的检测方法的开发中的最新概念以及所选实例。