Microalgae have expanded their roles as renewable and sustainable feedstocks for biofuel, smart nutrition, biopharmaceutical, cosmeceutical, biosensing, and space technologies. They accumulate valuable biochemical compounds from protein, carbohydrate, and lipid groups, including pigments and carotenoids. Microalgal biomass, which can be adopted for multivalorization under biorefinery settings, allows not only the production of various biofuels but also other value‐added biotechnological products. However, state‐of‐the‐art technologies are required to optimize yield, quality, and the economical aspects of both upstream and downstream processes. As such, the need to use microfluidic‐based devices for both fundamental research and industrial applications of microalgae, arises due to their microscale sizes and dilute cultures. Microfluidics‐based devices are superior to their competitors through their ability to perform multiple functions such as sorting and analyzing small amounts of samples (nanoliter to picoliter) with higher sensitivities. Here, we review emerging applications of microfluidic technologies on microalgal processes in cell sorting, cultivation, harvesting, and applications in biofuels, biosensing, drug delivery, and nutrition.

中文翻译：

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用于微藻生物技术的微流体

微藻已扩大其作为生物燃料、智能营养、生物制药、药妆、生物传感和空间技术的可再生和可持续原料的作用。它们从蛋白质、碳水化合物和脂质组中积累有价值的生化化合物，包括色素和类胡萝卜素。微藻生物质可用于生物炼制环境下的多价化，不仅可以生产各种生物燃料，还可以生产其他增值生物技术产品。然而，需要最先进的技术来优化上游和下游工艺的产量、质量和经济方面。因此，由于它们的微尺度尺寸和稀释的培养物，需要使用基于微流体的设备进行微藻的基础研究和工业应用。基于微流体的设备优于其竞争对手，因为它们能够执行多种功能，例如以更高的灵敏度分类和分析少量样品（纳升到皮升）。在这里，我们回顾了微流体技术在细胞分选、培养、收获和生物燃料、生物传感、药物输送和营养等微藻过程中的新兴应用。