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Sexual orientation and gender identity disparities in co-occurring depressive symptoms and probable substance use disorders in a national cohort of young adults
Addictive Behaviors ( IF 4.4 ) Pub Date : 2021-01-07 , DOI: 10.1016/j.addbeh.2021.106817
Jennifer K Felner 1 , Sean J Haley 2 , Hee-Jin Jun 1 , Jennifer P Wisdom 3 , Laura Katuska 4 , Heather L Corliss 1
Affiliation  

This study examined sexual orientation and gender identity differences in co-occurring depressive symptoms and substance use disorders (SUDs) among young adults in the Growing Up Today Study national cohort (n = 12,347; ages 20–35; 93% non-Hispanic white). Self-administered questionnaires assessed recent co-occurring depressive symptoms and probable nicotine dependence, alcohol use disorder, and drug use disorder. Multinomial logistic regressions with generalized estimating equations quantified differences in prevalences of depressive symptoms only, SUDs only, and co-occurrence, among sexual minorities (mostly heterosexual; lesbian, gay, and bisexual [LGB]) compared to completely heterosexual participants, and gender minorities compared to cisgender participants. Analyses stratified by sex assigned at birth revealed sexual minorities evidenced greater odds of co-occurrence than their completely heterosexual counterparts (assigned female AORs: 3.11–9.80, ps < 0.0001; assigned male AORs: 2.90–4.87, ps < 0.001). Sexual orientation differences in co-occurrence were pronounced among LGB participants assigned female at birth who evidenced nearly 10 times the odds of co-occurring depressive symptoms with nicotine dependence and drug use disorders than did heterosexual participants assigned female at birth. Relationships between gender identity and co-occurrence were generally weaker, possibly due to low power. Gender minorities assigned male at birth, however, evidenced greater odds of co-occurring depressive symptoms and alcohol use disorders (AOR 2.75, p = 0.013) than their cisgender counterparts. This study adds to the limited research quantifying sexual orientation or gender identity differences in recent co-occurring depressive symptoms and SUDs among young adults and suggests sexual and gender minority young adults should be prioritized in prevention and treatment of co-occurring depression and SUDs.



中文翻译:

全国青年队列中同时出现的抑郁症状和可能的物质使用障碍的性取向和性别认同差异

本研究调查了“今日成长研究”国家队列(n = 12,347;20-35 岁;93% 非西班牙裔白人)中年轻人同时出现的抑郁症状和物质使用障碍 (SUDs) 的性取向和性别认同差异. 自我管理的问卷评估了近期同时出现的抑郁症状和可能的尼古丁依赖、酒精使用障碍和药物使用障碍。具有广义估计方程的多项逻辑回归量化了性少数群体(主要是异性恋;女同性恋、男同性恋和双性恋 [LGB])与完全异性恋参与者和性别少数群体在抑郁症状、SUD 和共现方面的患病率差异与顺性别参与者相比。按出生时分配的性别分层的分析显示,性少数群体比完全异性恋的同龄人表现出更大的共同发生几率(分配的女性 AOR:3.11-9.80,ps < 0.0001;分配的男性 AOR:2.90-4.87,ps < 0.001)。在出生时被分配为女性的 LGB 参与者中,共同发生的性取向差异很明显,他们证明与尼古丁依赖和药物使用障碍共同发生的抑郁症状的几率是出生时分配为女性的异性恋参与者的近 10 倍。性别认同和共现之间的关系通常较弱,可能是由于权力低。然而,性别少数群体在出生时被分配为男性,与顺性别者相比,他们同时出现抑郁症状和酒精使用障碍的几率更大(AOR 2.75,p = 0.013)。

更新日期:2021-02-21
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