Polydopamine (PDA) films allow to functionalize almost all materials with a conformal and chemically active coating. These coatings can react with reducible metallic cations and with all kinds of molecules carrying nucleophilic groups. Recently, our team extended PDA chemistry to a vast repertoire of oxidants and to acidic conditions. However, the influence of changes in the method of PDA deposition on the properties of the obtained coatings, in particular the antioxidant properties, have not been sufficiently explored. It is anticipated that the antioxidant properties should depend on the film preparation method. A combination of experimental techniques, atomic force microscopy, cyclic voltammetry and X ray photoelectron spectroscopy are used to relate the antioxidant properties of PDA films to their structural features and to their chemical composition. It is demonstrated that the antioxidant properties of PDA films are not only dependent on the type of the employed oxidant – which can be expected to affect a variable density of oxidizable groups on the surface of PDA - but also on the oxidant film morphology and roughness.

聚多巴胺（PDA）薄膜可通过保形和化学活性涂层使几乎所有材料功能化。这些涂层可以与可还原的金属阳离子以及所有带有亲核基团的分子发生反应。最近，我们的团队将PDA化学扩展到了广泛的氧化剂和酸性条件。然而，尚未充分探讨PDA沉积方法的变化对所得涂层的性能，特别是抗氧化剂性能的影响。预期抗氧化剂性质应取决于膜的制备方法。实验技术，原子力显微镜的结合，循环伏安法和X射线光电子能谱用于将PDA薄膜的抗氧化性能与其结构特征和化学组成相关联。结果表明，PDA薄膜的抗氧化性能不仅取决于所用氧化剂的类型（可以预期会影响PDA表面可变密度的可氧化基团），还取决于氧化剂薄膜的形貌和粗糙度。