Because of their role of information transmitter between the spinal cord and the muscle fibers, motor neurons are subject to physical stimulation and mechanical properties modifications. We report on motoneuron elasticity investigated by time resolved pump and probe spectroscopy. A dual picosecond geometry probing simultaneously the acoustic impedance mismatch at the cell/Titanium transducer interface and acoustic wave propagation inside the motoneuron is presented. Such non- contact/non-destructive microscopy, correlated to standard atomic force microscopy or fluorescent labels approach have been carried out on a single cell to address some physical properties as bulk modulus of elasticity, dynamical longitudinal viscosity or adhesion.

中文翻译：

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泵浦和探针光谱法对运动神经元细胞弹性的相关成像

由于它们在脊髓和肌纤维之间的信息传递作用，运动神经元受到物理刺激和机械性能的改变。我们报告了通过时间分辨泵和探针光谱研究的运动神经元弹性。提出了一种双皮秒几何结构，同时探测细胞/钛换能器界面处的声阻抗失配和运动神经元内的声波传播。这种与标准原子力显微镜或荧光标记方法相关的非接触/非破坏性显微镜已在单个细胞上进行，以解决一些物理特性，如弹性体积模量、动态纵向粘度或粘附力。